skip to main content


Search for: All records

Creators/Authors contains: "Ludwig, Andrew"

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. Free, publicly-accessible full text available July 25, 2024
  2. Free, publicly-accessible full text available July 25, 2024
  3. The Beamforming Elevated Array for COsmic Neutrinos (BEACON) is a concept for a neutrino telescope designed to measure tau lepton air showers generated from tau neutrino interactions near the horizon. This detection mechanism provides a pure measurement of the tau flavor of cosmogenic neutrinos, which could be used to set limits on the observed flavor ratios for cosmogenic neutrinos in a manner complimentary to the all-flavor neutrino flux measurements made by other experiments. BEACON is expected to also be capable of detecting cosmic rays through RF-only triggers. BEACON aims to achieve this sensitivity by using mountaintop radio arrays of dual-polarized antennas operating in the 30-80 MHz band which utilize directional interferometric triggering. BEACON stations are designed to efficiently use a small amount of instrumentation, allowing for deployment in a variety of high-elevation sites. The interferometric trigger provides a natural tool for directional-based anthropogenic RFI rejection at the trigger level, broadening the list for potential station sites. The BEACON prototype has seen continuous design advancements towards improving the mechanical durability and scientific capabilities since its initial deployment at White Mountain Research Station in 2018. Here we present the current prototype’s sensitivity to RF-triggered cosmic-ray background signals. We also present the next generation prototype, which includes scintillating cosmic ray detectors, improved antennas, and refined calibration techniques. 
    more » « less
  4. Malik, Harmit S. (Ed.)
    Comparative genomics has enabled the identification of genes that potentially evolved de novo from non-coding sequences. Many such genes are expressed in male reproductive tissues, but their functions remain poorly understood. To address this, we conducted a functional genetic screen of over 40 putative de novo genes with testis-enriched expression in Drosophila melanogaster and identified one gene, atlas , required for male fertility. Detailed genetic and cytological analyses showed that atlas is required for proper chromatin condensation during the final stages of spermatogenesis. Atlas protein is expressed in spermatid nuclei and facilitates the transition from histone- to protamine-based chromatin packaging. Complementary evolutionary analyses revealed the complex evolutionary history of atlas . The protein-coding portion of the gene likely arose at the base of the Drosophila genus on the X chromosome but was unlikely to be essential, as it was then lost in several independent lineages. Within the last ~15 million years, however, the gene moved to an autosome, where it fused with a conserved non-coding RNA and evolved a non-redundant role in male fertility. Altogether, this study provides insight into the integration of novel genes into biological processes, the links between genomic innovation and functional evolution, and the genetic control of a fundamental developmental process, gametogenesis. 
    more » « less
  5. null (Ed.)